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Linezolid Oral

Generic Name: LINEZOLID SUSPENSION - ORAL
Pronounced: (lin-AZE-oh-lid)

Linezolid Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • atomoxetine
  • bethanidine
  • bupropion
  • buspirone
  • carbamazepine
  • dextromethorphan
  • certain antihistamines (azatadine, carbetapentane, chlorpheniramine)
  • certain eye drops (apraclonidine, brimonidine)
  • herbal products (e.g., ephedra/ma huang)
  • methyldopa
  • certain narcotic pain relievers (fentanyl, meperidine)
  • papaverine
  • drugs for Parkinson's disease (such as entacapone, tolcapone)
  • reboxetine
  • SSRI antidepressants (e.g., fluoxetine, citalopram)
  • sympathomimetics (e.g., ephedrine, methylphenidate)
  • tetrabenazine
  • tramadol
  • tricyclic antidepressants (e.g., amitriptyline, doxepin)
  • "triptans" (e.g., sumatriptan, zolmitriptan)
  • weight loss drugs (such as sibutramine)


Avoid taking other MAO inhibitors (e.g., furazolidone, isocarboxazid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during, and after treatment with this medication.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting linezolid.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • bethanidine
  • indoramin
  • inhaled bronchodilators (e.g., albuterol, salmeterol)
  • levodopa
  • other drugs which depress the bone marrow (e.g., cancer chemotherapy)
  • other herbals (such as ginseng, tryptophan)


Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Avoid these products while taking this medication. Ask your pharmacist for additional information.

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