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Easy Sleep Oral

Generic Name: DIPHENHYDRAMINE - ORAL
Pronounced: (dye-fen-HI-druh-meen)

Easy Sleep Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) for 2 weeks before, during, and 2 weeks after treatment with this medication. In some cases a serious, possibly fatal, drug interaction may occur.



Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • antispasmodics (e.g., atropine, belladonna alkaloids)
  • drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl)
  • scopolamine
  • tricyclic antidepressants (e.g., amitriptyline)


Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., dimenhydrinate), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

Check the labels on all your medicines because they may also contain diphenhydramine or other antihistamines (e.g., dimenhydrinate). This includes medications taken by mouth or applied to the skin (e.g., anti-itch cream, ointment, spray). Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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