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Thioridazine Oral

Generic Name: THIORIDAZINE - ORAL
Pronounced: (thigh-oh-RID-uh-zeen)

Thioridazine Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • cabergoline
  • cisapride
  • duloxetine
  • certain SSRI antidepressants (e.g., fluoxetine, fluvoxamine, paroxetine)
  • pergolide
  • pindolol
  • propranolol
  • sibutramine


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting thioridazine.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • anticholinergic medications (e.g., belladonna alkaloids, atropine, scopolamine)
  • carbamazepine
  • guanethidine
  • guanadrel
  • lithium
  • medications for Parkinson's disease (e.g., levodopa, benztropine)
  • certain "water pills" (potassium-wasting diuretics such as hydrochlorothiazide, furosemide)


This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • amiodarone
  • bepridil
  • disopyramide
  • dofetilide
  • droperidol
  • halofantrine
  • pimozide
  • sparfloxacin
  • ziprasidone


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting thioridazine. Other drugs besides thioridazine and those listed above which may affect the heart rhythm (QT prolongation in the EKG) include quinidine, sotalol, procainamide, and erythromycin, among others. Before using thioridazine, report all medications you are currently using to your doctor or pharmacist. QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (e.g., severe dizziness, fainting) that require immediate medical attention. Ask your doctor or pharmacist for more details and for instructions on how you may reduce the risk of this effect.

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