Comazol Oral

In Depth

Generic Name: PROCHLORPERAZINE - ORAL
Pronounced: (pro-klor-PAIR-uh-zeen)

Comazol Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

dofetilide
certain drugs that increase dopamine activity (e.g., cabergoline, pergolide)
certain drugs that may affect the heart rhythm (e.g., cisapride, halofantrine, sparfloxacin, pimozide)
epinephrine for low blood pressure
metrizamide
sibutramine

If you currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially:

alpha blockers (e.g., prazosin)
anticholinergics (e.g., atropine, scopolamine)
anti-seizure drugs (e.g., carbamazepine)
guanethidine/guanadrel
narcotic pain relievers (e.g., codeine)

Also report the use of drugs which might increase seizure risk when combined with prochlorperazine such as bupropion, isoniazid (INH), other phenothiazines (e.g., thioridazine), theophylline, tramadol, tricyclic antidepressants (e.g., amitriptyline) among others. Consult your doctor or pharmacist for details.

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

This medication can affect the results of certain lab tests (e.g., phenylketonuria, certain pregnancy tests, certain urine tests such as amylase). Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.