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Aspirin W/Codeine Oral

Generic Name: ASPIRIN/CODEINE - ORAL
Pronounced: (AS-pir-in/KO-deen)

Aspirin W/Codeine Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur:

  • mifepristone
  • naltrexone
  • ketorolac


If you are currently using any of these medications, tell your doctor or pharmacist before starting this product.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • ACE inhibitors (such as captopril, lisinopril)
  • carbonic anhydrase inhibitors (such as acetazolamide)
  • bisphosphonates taken by mouth (such as alendronate)
  • "blood thinners" (such as warfarin, enoxaparin, clopidogrel)
  • corticosteroids (such as prednisone, dexamethasone)
  • certain antidepressants (SSRIs such as fluoxetine/sertraline, SNRIs such as duloxetine)
  • certain drugs to treat diabetes (sulfonylureas such as glyburide/glipizide)
  • certain medications for gout (probenecid, sulfinpyrazone)
  • ginkgo biloba
  • mercaptopurine
  • methotrexate
  • certain medications for pain (opiate partial agonists such as butorphanol, nalbuphine, pentazocine)
  • pemetrexed
  • quinidine
  • salicylates (such as salsalate)
  • valproic acid


The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also affect breathing or cause drowsiness. Therefore, tell your doctor or pharmacist if you are taking other products such as alcohol, anti-seizure drugs (such as phenobarbital), medicine for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, other narcotic pain relievers (such as morphine), and psychiatric medicines (such as risperidone, amitriptyline, trazodone). Your medications or doses of your medications may need to be changed.

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