Pacerone Oral
Generic Name: AMIODARONE - ORAL
Pronounced: (A-mi-OH-da-rone)
Pacerone Oral Interactions
See also Warning and How to Use sections.
Your doctor or pharmacist may already be aware of any possible
drug interactions and may be monitoring you for them. Do not start,
stop, or change the dosage of any medicine before checking with
them first.
This drug should not be used with the following medications
because very serious interactions may occur:
- agalsidase
- dofetilide
- certain HIV protease inhibitors (indinavir, nelfinavir,
ritonavir, saquinavir)
- quinupristin/dalfopristin
If you are currently using any of these medications, tell your
doctor or pharmacist before starting amiodarone.
Other drugs besides amiodarone that may affect the heart rhythm
(QT prolongation in the EKG) include other antiarrhythmics (e.g.,
flecainide, procainamide, quinidine, sotalol), macrolide
antibiotics (e.g., erythromycin), pimozide, and quinolone
antibiotics (e.g., levofloxacin), among others. Before using
amiodarone, report all medications you are currently using to your
doctor or pharmacist. QT prolongation can infrequently result in
serious (rarely fatal) fast/irregular heartbeat and other symptoms
(e.g., severe dizziness, fainting) that require immediate medical
attention. Ask your doctor or pharmacist for more details and for
instructions on how you may reduce the risk of this effect.
Before using this medication, tell your doctor or pharmacist of
all prescription and nonprescription/herbal products you may use,
especially of:
- clopidogrel
- certain "water pills" (potassium-wasting diuretics such as
hydrochlorothiazide, furosemide)
- drugs affecting liver enzymes that remove amiodarone from
your body (such as azole antifungals including itraconazole,
cimetidine, fentanyl, lidocaine, rifampin, St. John's wort,
trazodone, certain anti-seizure medicines including
phenytoin)
Amiodarone can slow down the removal of other drugs from your
body by affecting certain liver enzymes. These affected drugs
include (this is not a complete list): beta blockers (e.g.,
propranolol), calcium channel blockers (e.g., diltiazem,
verapamil), cyclosporine, certain cholesterol-lowering "statins"
(atorvastatin, lovastatin, simvastatin), digoxin, tizanidine,
warfarin, drugs to treat erectile dysfunction (e.g., sildenafil,
tadalafil, vardenafil).
This document does not contain all possible interactions.
Therefore, before using this product, tell your doctor or
pharmacist of all the products you use. Keep a list of all your
medications with you, and share the list with your doctor and
pharmacist.
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