Bupropion Oral
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (byou-PRO-pee-on)
Bupropion Oral Interactions
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.
This drug should not be used with the following medications because very serious interactions may occur:
- MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, isocarboxazid, tranylcypromine)
- certain x-ray dyes such as iomeprol
- sibutramine
- thioridazine
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting bupropion.
If you are currently using or have recently stopped taking an MAO inhibitor within the last 14 days, tell your doctor or pharmacist before starting bupropion.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of:
- amantadine
- diabetes medications (e.g., hypoglycemic agents such as glyburide, glipizide, or insulin)
- HIV drugs (e.g., efavirenz, nelfinavir, ritonavir)
- levodopa
- nicotine products (e.g., patches, gum, or spray)
- regular use of sedatives (e.g., alcohol, alprazolam)
- stimulants (e.g., amphetamine, cocaine, "ecstasy," ephedrine)
- warfarin
Also tell your doctor if you are taking any drugs which are affected by certain liver enzymes such as antidepressants (e.g., desipramine, paroxetine, fluoxetine, sertraline), antipsychotics (e.g., haloperidol), beta-blockers (e.g., metoprolol), antiarrhythmics (e.g., propafenone, flecainide), orphenadrine, thiotepa, cyclophosphamide, carbamazepine, phenobarbital, or phenytoin.
Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with bupropion such as phenothiazines (e.g., chlorpromazine), tricyclic antidepressants (e.g., amitriptyline), corticosteroids (e.g., prednisone), or theophylline among others. Consult your doctor or pharmacist for details.
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