Niacin-Lovastatin Oral

In Depth

Generic Name: NIACIN EXTENDED-RELEASE/LOVASTATIN - ORAL
Pronounced: (NYE-a-sin/LOW-vuh-stat-in)

Niacin-Lovastatin Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

See also How to Use section.

This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur:

certain azole antifungals (itraconazole, ketoconazole)
delavirdine
HIV protease inhibitors (e.g., ritonavir, amprenavir, lopinavir, nelfinavir)
certain macrolide antibiotics (erythromycin, clarithromycin, troleandomycin)
nefazodone
telithromycin

If you are currently using any of these medications, tell your doctor or pharmacist before starting this product.

Infrequently, muscle problems (myopathy) may occur when this product is used with certain other drugs that lower cholesterol/triglycerides. Use caution if you are taking the following drugs along with this product, and tell your doctor immediately if any muscle problems occur (see also Side Effects section):

fibrates (e.g., gemfibrozil, fenofibrate)

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

alpha blockers (e.g., prazosin)
azithromycin
"blood thinners" (e.g., warfarin)
daptomycin
drugs affecting liver enzymes that remove lovastatin from your body (such as azole antifungals including fluconazole/voriconazole/posaconazole, amiodarone, cyclosporine, danazol, diltiazem, verapamil, rifampin, St. John's wort, carbamazepine)
drugs to treat high blood pressure (e.g., ACE inhibitors such as lisinopril, beta blockers such as atenolol)
nitrates (e.g., isosorbide dinitrate)
vitamin or dietary products that contain niacin or nicotinamide

This product can affect the results of certain lab tests (e.g., urine or blood catecholamines, copper-based urine glucose tests). Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.