Mycobutin Oral

Mycobutin Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur:

• delavirdine
• voriconazole

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting rifabutin.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• HIV protease inhibitors (e.g., indinavir, ritonavir, nelfinavir)
• clarithromycin
• itraconazole
• fluconazole
• estrogens

Rifabutin is similar to another antibiotic, rifampin, which can speed up the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include erythromycin, fluoroquinolones (e.g., ciprofloxacin), ketoconazole, certain other HIV-medications (e.g., efavirenz, nevirapine), doxycycline, chloramphenicol, mefloquine, atovaquone, tamoxifen, thyroid, levothyroxine, warfarin, cyclosporine, tacrolimus, corticosteroids (e.g., prednisone, dexamethasone), phenytoin, lamotrigine, barbiturates (e.g., phenobarbital), calcium channel blockers (e.g., verapamil, nifedipine), propranolol, metoprolol, enalapril, losartan, digoxin, mexiletine, propafenone, antidiabetics (e.g., glyburide, glimepiride, repaglinide), simvastatin, fluvastatin, nortriptyline, haloperidol, quetiapine, benzodiazepines (e.g., diazepam, triazolam), buspirone, zolpidem, sunitinib, erlotinib, irinotecan.

This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Previous Section

Precautions and Side Effects