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Sulfasalazine Oral

Generic Name: SULFASALAZINE - ORAL
Pronounced: (sull-fuh-SAL-uh-zeen)

Sulfasalazine Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because very serious interactions may occur:

  • methenamine


If you are currently using the medication listed above, tell your doctor or pharmacist before starting sulfasalazine.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • cyclosporine
  • digoxin
  • folic acid
  • certain drugs used to treat diabetes (sulfonylureas such as glipizide, glyburide, tolbutamide)
  • PABA taken by mouth
  • phenytoin
  • warfarin


This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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