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Cyclobenzaprine Oral

Generic Name: CYCLOBENZAPRINE - ORAL
Pronounced: (sye-klo-BENZ-uh-preen)

Cyclobenzaprine Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) within 2 weeks before starting or after stopping treatment with this medication. In some cases, a serious, possibly fatal, drug interaction may occur.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • certain types of asthma drugs (e.g., albuterol, salmeterol)
  • cimetidine
  • clonidine
  • guanethidine
  • guanadrel
  • SSRI antidepressants (e.g., fluoxetine, citalopram)
  • stimulants and weight loss products (e.g., ephedrine, dextroamphetamine, phenylephrine)
  • tramadol
  • tricyclic antidepressants (e.g., amitriptyline, imipramine)


Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: anti-anxiety drugs (e.g., diazepam), antihistamines that cause drowsiness (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep (e.g., sedatives), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines such as chlorpromazine), tranquilizers.

Check all prescription and nonprescription medicine labels (e.g., cough-and-cold products, diet aids, acid reducers) because they may contain ingredients which could increase the risk of side effects with cyclobenzaprine. Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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