Nefazodone Oral

In Depth

Generic Name: NEFAZODONE - ORAL
Pronounced: (neh-FAZZ-oh-doan)

Nefazodone Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur:

carbamazepine
cisapride
eplerenone
ivabradine
pimozide
sibutramine

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before and during treatment and within 1 week after treatment with this medication. In some cases a serious (possibly fatal) drug interaction may occur.

Avoid taking eletriptan within 72 hours of taking this medication.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting nefazodone.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

alpha blockers (e.g., terazosin)
digoxin
drugs removed from your body by certain liver enzymes (e.g., "statin" cholesterol drugs such as simvastatin/lovastatin/atorvastatin, tacrolimus, cyclosporine, buspirone, dasatinib, sunitinib, fentanyl, certain benzodiazepines such as alprazolam/triazolam/diazepam)
fluoxetine
medications for high blood pressure
other antidepressants (e.g., trazodone, SSRIs such as fluoxetine)
other drugs that can cause bleeding/bruising (e.g., anticoagulants such as heparin or warfarin, antiplatelet drugs including NSAIDs such as ibuprofen)

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., phenytoin), medicine for sleep (e.g., zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, haloperidol).

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