Biaxin Oral
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (kluh-RITH-row-MY-sin)
Biaxin Oral Interactions
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.
This drug should not be used with the following medications because very serious interactions may occur:
- eletriptan
- eplerenone
- ergot alkaloids (e.g., ergotamine, dihydroergotamine)
- ivabradine
- quinupristin-dalfopristin
- ranolazine
If you are currently using any of these medications, tell your doctor or pharmacist before starting clarithromycin.
Many drugs besides clarithromycin may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, quinidine, sotalol, pimozide, procainamide, moxifloxacin, gatifloxacin, propafenone, thioridazine, macrolide antibiotics (such as erythromycin), among others. Therefore, before using clarithromycin, report all medications you are currently using to your doctor or pharmacist.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:
- drugs affecting liver enzymes that remove clarithromycin from your body (such as rifamycins - including rifabutin and rifampin, and azole antifungals - including itraconazole and fluconazole)
- certain HIV medications (e.g., zidovudine, delavirdine, protease inhibitors such as atazanavir, ritonavir)
- certain anti-seizure medications (e.g., carbamazepine, phenytoin, valproate)
- blood thinners (e.g., warfarin)
- colchicine
- digoxin
- live bacterial vaccines
This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes. Some examples of these affected drugs include alfentanil, certain benzodiazepines (e.g., alprazolam, midazolam, triazolam), bromocriptine, cilostazol, corticosteroids (e.g., methylprednisolone), cyclosporine, disopyramide, fentanyl, repaglinide, sildenafil, certain statins (atorvastatin, lovastatin, simvastatin), tacrolimus, tolterodine, theophylline.
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