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Vicoprofen Oral

Generic Name: HYDROCODONE/IBUPROFEN - ORAL
Pronounced: (hye-droe-KOE-done eye-byou-PRO-fen)

Vicoprofen Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • cidofovir
  • ketorolac
  • naltrexone


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • anticholinergic drugs (e.g., atropine, scopolamine)
  • anti-platelet drugs (e.g., cilostazol, clopidogrel)
  • bisphosphonates taken by mouth (e.g., alendronate)
  • "blood thinners" (e.g., enoxaparin, heparin, warfarin)
  • cimetidine
  • corticosteroids (e.g., prednisone)
  • cyclosporine
  • desmopressin
  • digoxin
  • drugs for high blood pressure (including ACE inhibitors such as captopril, angiotensin II receptor antagonists such as losartan, and beta blockers such as metoprolol)
  • lithium
  • MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine)
  • methotrexate
  • other medications for pain (e.g., codeine, nalbuphine)
  • pemetrexed
  • probenecid
  • SSRI antidepressants (e.g., fluoxetine, sertraline)
  • tenofovir
  • "water pills" (diuretics such as furosemide, hydrochlorothiazide, triamterene)


Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, psychiatric medicines (e.g., risperidone, amitriptyline, trazodone).

Check all prescription and nonprescription medicine labels carefully for other pain/fever drugs (NSAIDs such as aspirin, celecoxib, naproxen). These drugs are similar to ibuprofen, so taking one of these drugs while also taking ibuprofen may increase your risk of side effects. Consult your doctor or pharmacist for more details.

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