Librax (with Clinidium) Oral

Librax (with Clinidium) Oral Interactions

See also the How to Use section.

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include:

• potassium tablets/capsules
• sodium oxybate
• drugs that are affected by slowed gut movement (such as metoclopramide, pramlintide)

This medication may affect the absorption of other products such as levodopa, certain azole anti-fungal drugs (ketoconazole, itraconazole), slowly-dissolving forms of digoxin, among others. If you are taking either ketoconazole or itraconazole, take it at least 2 hours before this medication.

Other medications can affect the removal of chlordiazepoxide from your body, which may affect how this drug works. Examples include cimetidine, disulfiram, among others.

Cigarette smoking decreases blood levels of chlordiazepoxide. Tell your doctor if you smoke or if you have recently stopped smoking.

Many other drugs that also cause dry mouth and constipation may interact with anticholinergics/antispasmodics such as clidinium. Tell your doctor or pharmacist about all the products you take, including:

• amantadine
• other anticholinergic drugs (such as atropine, glycopyrrolate, scopolamine)
• other antispasmodic drugs (such as dicyclomine, propantheline)
• belladonna alkaloids
• certain drugs used to treat Parkinson's disease (such as benztropine, trihexyphenidyl)
• certain drugs used to treat irregular heart rhythms (such as disopyramide, quinidine)
• MAO inhibitors (isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine)
• phenothiazines (such as chlorpromazine)
• tricyclic antidepressants (such as amitriptyline)

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