Aldactazide Oral
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (THIGH-uh-zide/SPY-row-no-lack-tone)
Aldactazide Oral Interactions
See also How to Use section.
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
This drug should not be used with the following medications because very serious interactions may occur:
- dofetilide
- tacrolimus
If you are currently using any of these medications, tell your doctor or pharmacist before starting spironolactone with hydrochlorothiazide.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:
- alcohol
- barbiturates (e.g., phenobarbital)
- cisapride
- diazoxide
- digoxin
- drugs for diabetes (e.g., glyburide, insulin)
- certain hormones (ACTH)
- lithium
- mitotane
- narcotic pain relievers (e.g., codeine)
- norepinephrine
- skeletal muscle relaxants (e.g., tubocurarine)
- drugs that cause potassium loss (e.g., amphotericin B, corticotropin, corticosteroids including prednisone)
- drugs whose removal from the body is affected by the acid level in urine (e.g., amphetamine, methenamine)
This medication may increase your potassium levels. Using this product with other medications that increase your potassium levels may cause very serious (possibly fatal) side effects. These medications include:
- ACE inhibitors (e.g., captopril, enalapril)
- ARBs (e.g., candesartan, losartan)
- drospirenone
- eplerenone
- nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, indomethacin, naproxen)
- other water pills that may increase your potassium level, including amiloride
- potassium-containing products (e.g., salt substitutes)
- potassium supplements
Limit foods high in potassium such as bananas, potatoes, cantaloupe, citrus fruits, dates, prunes, avocado, raisins, cooked spinach, lentils and low-salt milk. These foods may increase your potassium levels if eaten in large amounts. Discuss with your doctor or nutritionist.
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