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Synthroid Inj

Generic Name: LEVOTHYROXINE - INJECTION
Pronounced: (lev-oh-thigh-ROX in)

Synthroid Inj Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • androgens/anabolic steroids (e.g., testosterone)
  • antidepressants (e.g., SSRIs such as sertraline, tricyclics such as amitriptyline)
  • beta blockers (e.g., propranolol)
  • corticosteroids (e.g., dexamethasone)
  • cytokines (e.g., interferon alfa, interleukin-2)
  • digoxin
  • drugs to treat diabetes (e.g., insulin, sulfonylureas such as glyburide)
  • epinephrine
  • estrogen-containing products (e.g., birth control pills, hormone replacement therapy)
  • ketamine
  • theophylline
  • warfarin
  • drugs that can decrease thyroid hormone levels (e.g., amiodarone, medications containing iodide/iodine, lithium)
  • drugs affecting liver enzymes that remove levothyroxine from your body (e.g., phenobarbital, rifamycins including rifampin, certain anti-seizure medicines including carbamazepine and phenytoin)


High doses of salicylates (e.g., high doses of aspirin) may affect thyroid hormone levels in the blood. However, low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day). Ask your doctor or pharmacist for more details.

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients such as decongestants or caffeine that could increase your heart rate or blood pressure. Ask your pharmacist about using those products safely.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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