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Ludiomil Oral

Generic Name: MAPROTILINE - ORAL
Pronounced: (map-ROW-till-een)

Ludiomil Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during, and after treatment with this medication. In some cases a serious (possibly fatal) drug interaction may occur.

This drug should not be used with the following medications because very serious interactions may occur:

  • cisapride
  • disopyramide
  • sibutramine


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting maprotiline.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • alcohol
  • anticholinergic drugs (e.g., atropine, benztropine, oxybutynin, trihexyphenidyl)
  • benzodiazepines (e.g., diazepam, lorazepam, triazolam)
  • drugs affecting liver enzymes that remove maprotiline from your body (e.g., cimetidine, fluoxetine, phenytoin, terbinafine, barbiturates including phenobarbital)
  • drugs that increase the risk of seizures (e.g., bupropion, tramadol)
  • gatifloxacin
  • guanadrel
  • guanethidine
  • phenothiazines (e.g., chlorpromazine)
  • stimulants (e.g., amphetamine, methylphenidate)
  • sympathomimetics (e.g., albuterol, pseudoephedrine)
  • thyroid medication


This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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