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Ludiomil Oral

Generic Name: MAPROTILINE - ORAL
Pronounced: (map-ROW-till-een)

Ludiomil Oral Interactions

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include:

  • arbutamine
  • levodopa
  • sibutramine
  • bronchodilators/decongestants (such as albuterol, epinephrine, phenylephrine)
  • stimulants (such as amphetamines, methylphenidate, streets drugs including MDMA/"ecstasy")
  • thyroid supplements
  • anticholinergic drugs (such as benztropine, belladonna alkaloids)
  • central-acting drugs to treat high blood pressure (such as clonidine, guanabenz, guanadrel, methyldopa, reserpine)


Avoid taking MAO inhibitors (isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during, and after treatment with this medication. In some cases a serious (possibly fatal) drug interaction may occur.

Other medications can affect the removal of maprotiline from your body, thereby affecting how maprotiline works. These drugs include cimetidine, fluconazole, terbinafine, drugs to treat irregular heart rate (such as quinidine/propafenone/flecainide), antidepressants (such as SSRIs including paroxetine/fluoxetine/fluvoxamine). This is not a complete list.

If you have been taking fluoxetine, wait at least 5 weeks before starting maprotiline.

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