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Dactinomycin IV

Generic Name: DACTINOMYCIN - INJECTION
Pronounced: (dack-tin-oh-MY-sin)

Dactinomycin IV Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:



  • live vaccines (e.g., flu vaccine inhaled through the nose, typhoid/polio vaccine taken by mouth)


If you are currently receiving or planning any vaccinations, tell your doctor or pharmacist before starting dactinomycin.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • "blood thinners" (e.g., warfarin, enoxaparin)
  • salicylates/NSAIDs (e.g., aspirin, ibuprofen, naproxen, sodium salicylate)


Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, and aspirin) that can increase your risk of bleeding. Low-dose aspirin should be continued if prescribed by your doctor for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day). Consult your doctor or pharmacist for more details.

This product can affect the results of certain lab tests (e.g., antibiotic drug levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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