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Lexiva Oral

In Depth

Generic Name: FOSAMPRENAVIR - ORAL
Pronounced: (fos-am-PREN-uh-veer)

Lexiva Oral Side Effects

Diarrhea, nausea, vomiting, headache, fatigue, and stomach/abdominal pain may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • unusual increase in thirst or urination
  • mental/mood changes
  • numbness or tingling of hands or feet
  • symptoms of kidney stones (such as pain in your side, blood in your urine, pain when urinating)


Seek immediate medical attention if any of these rare but serious side effects occur:

  • symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating)


Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect.

If you are taking HIV medications for the first time, you may experience symptoms of an old infection. This may happen as your immune system begins to work better. Contact your doctor immediately if you notice any of the following symptoms:

  • new cough
  • trouble breathing
  • fever
  • new vision problems
  • new headaches
  • new skin problems


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This medication can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Therefore, seek immediate medical attention if you develop any rash.

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