Surmontil Oral

In Depth

Generic Name: TRIMIPRAMINE - ORAL
Pronounced: (trye-MI-pra-meen)

Surmontil Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur:

arbutamine
sibutramine

Do not take this medication if you are taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) or have used MAO inhibitors within the 2 weeks before, during or after treatment with this medication. In some cases a serious, possibly fatal drug interaction may occur.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting trimipramine.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

anticholinergics (e.g., atropine, belladonna alkaloids)
bronchodilators/decongestants (e.g., albuterol, epinephrine, phenylephrine)
clonidine
certain drugs for high blood pressure (e.g., guanadrel, guanethidine, reserpine)
drugs affecting liver enzymes that remove this medication from your body (e.g., cimetidine, haloperidol, protease inhibitors such as amprenavir/fosamprenavir/ritonavir, drugs that affect heart rhythm such as flecainide/quinidine/propafenone, SSRI antidepressants such as paroxetine)
drugs for motion sickness (e.g., meclizine, scopolamine)
stimulants (e.g., amphetamines, methylphenidate)
St. Johns wort
thyroid medication

If you have been taking fluoxetine, wait at least 5 weeks after stopping fluoxetine before starting trimipramine.

Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with this medication such as bupropion, isoniazid (INH), phenothiazines (e.g., thioridazine), theophylline, tricyclic antidepressants (e.g., amitriptyline) or tramadol, among others. Consult your doctor or pharmacist for details.

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