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Claravis Oral

  • diabetes
  • family or personal history of high blood fats (triglycerides)
  • family or personal history of psychiatric disorders (including depression)
  • liver disease
  • obesity
  • eating disorders (e.g., anorexia nervosa)
  • alcohol abuse
  • pancreatitis
  • bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density)


Do not donate blood while you are taking isotretinoin and for at least 1 month after you stop taking it.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

Isotretinoin can affect your night vision. Do not drive, use machinery, or do any activity that requires clear vision after dark until you are sure you can perform such activities safely.

If you wear contact lenses, you may not tolerate them as well as usual while using this medication. Contact your doctor for more information.

Do not have cosmetic procedures to smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring may occur.

Avoid the use of alcohol while taking this medication because it may increase the risk of certain side effects (e.g., pancreatitis).

Limited information suggests isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal plate closure). Consult your doctor for more details.

Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially the effects on bones.

Caution is advised when using this drug in children because they may be more sensitive to its effects, especially back/joint/muscle pain.

This drug must not be used during pregnancy or by those who may become pregnant during treatment. If you become pregnant or think you may be pregnant, inform your doctor immediately. See also Warning section.

You must have two negative pregnancy tests before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is positive, you must stop taking this medication and consult your doctor immediately.

It is not known if this medication passes into breast milk. Due to the potential risks to the infant, do not breast-feed while using this medication.

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