pamidronate IV
In Depth
- Uses and How to Use
- Precautions and Side Effects
- Drug Interactions
- Dosage and Storage
- Drug Images
Pronounced: (pam-ih-DRO-nate)
pamidronate IV Uses
Pamidronate is used to treat high blood calcium levels and certain bone problems (bone metastases/lesions) that may occur with some types of cancer. It is also used to treat a certain type of bone disease (Paget's disease) that causes abnormal and weak bones.
Pamidronate belongs to a class of drugs known as bisphosphonates. It works by slowing the release of calcium from bones to lower blood calcium levels, reducing the risk of broken bones (fractures) and reducing bone pain.
How To Use pamidronate IV
This medication is given by a health care professional. It is diluted in sterile IV fluid and slowly injected into a vein for at least 2 hours, but up to 24 hours.
The dosage is based on your medical condition, laboratory tests, and response to treatment. Your doctor will order blood tests to check your kidney function prior to each treatment with this medication. The usual maximum adult dose of this medication is 90 milligrams for a single dose.
If you are being treated for a high blood calcium level, you may receive only a single dose of pamidronate. If you are being treated for cancer-related bone problems, you may receive a dose every 3 to 4 weeks. If you are being treated for Paget's disease, you may receive treatment daily for 3 days. Consult your doctor or pharmacist for more details.
During treatment with this medication, it is important that you take in plenty of fluids and pass urine frequently to help avoid kidney problems. Intravenous fluids are usually given with this medication. Ask your doctor how much fluid you should drink, and follow these instructions carefully.
It may take up to 7 days before the full benefit of this drug takes effect.
Tell your doctor if your condition does not improve or if it worsens.
