Naltrexone Oral

In Depth

Generic Name: NALTREXONE HCL - ORAL
Pronounced: (nal-TREX-own)

Naltrexone Oral Warning

Naltrexone can cause liver problems when given in large doses. Stop using this medication and tell your doctor immediately if symptoms of liver problems develop (e.g., persistent nausea, abdominal/stomach pain, yellowing eyes/skin, pale stools, dark urine).

This medication should not be used in patients who already have liver problems (e.g., active hepatitis, liver failure). (See also Side Effects section.)

Naltrexone Oral Side Effects

Nausea, headache, dizziness, anxiety, tiredness, and trouble sleeping may occur. In a small number of people, mild opiate withdrawal symptoms may occur, including abdominal cramps, restlessness, bone/joint pain, muscle aches, and runny nose. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Sudden opiate withdrawal symptoms can occur within minutes after taking naltrexone. Tell your doctor immediately if any of these withdrawal symptoms occur:

abdominal cramps
nausea/vomiting
diarrhea
joint/bone/muscle aches
mental/mood changes (e.g., anxiety, confusion, extreme sleepiness, visual hallucinations)
runny nose

Naltrexone has rarely caused serious liver disease. The risk is increased when larger doses are used. This increased risk is balanced by improved likelihood of taking this drug as directed and ease of use when this drug is taken less often (e.g., every other day). Discuss the risks and benefits with your doctor. (See also Warning section.)

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: