Zestoretic Oral
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (lyse-IN-oh-pril/HYE-droe-KLOR-oh-THYE-a-zide)
Zestoretic Oral Uses
This medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains 2 medications, lisinopril and hydrochlorothiazide. Lisinopril is called an ACE inhibitor and works by relaxing blood vessels so that blood can flow through the body more easily. Hydrochlorothiazide is called a "water pill" (diuretic) and causes your body to get rid of extra salt and water. This effect may increase the amount of urine you make when you first start the medication. It also helps to relax the blood vessels so that blood can flow through the body more easily.
These medications are used together when 1 drug is not controlling your blood pressure. Your doctor may direct you to start taking the individual medications first, and then switch you over to this combination product if this is the best dose combination for you. Do not continue taking the individual medications (lisinopril and/or hydrochlorothiazide) after you start this medication.
How To Use Zestoretic Oral
Take this medication by mouth with or without food, usually once daily or as directed by your doctor. If this medication causes you to urinate more frequently, then it is best to take this medication in the morning or during the day (at least 4 hours before your bedtime) to avoid having to get up during the night to urinate. Consult your doctor or pharmacist if you have questions about your dosing schedule.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. Also, keep your doses in a special pill box with 1 space marked for each day of the week. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
For the treatment of high blood pressure, it may take 2 to 4 weeks before the full benefit of this drug occurs. It may take several weeks or months to see the full benefit when this drug is used for heart failure.
Tell your doctor if your condition worsens (e.g., your routine blood pressure readings increase).







