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Zestoretic Oral

Generic Name: LISINOPRIL/HYDROCHLOROTHIAZIDE - ORAL
Pronounced: (lyse-IN-oh-pril/HYE-droe-KLOR-oh-THYE-a-zide)

Zestoretic Oral Warning

This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor immediately.

Zestoretic Oral Side Effects

Dizziness, lightheadedness, tiredness, or headache may occur as your body adjusts to the medication. Dry cough may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur:

  • fainting
  • muscle cramps/weakness
  • signs of infection (such as fever, chills, persistent sore throat)
  • slow/fast/irregular heartbeat
  • unusual decreased urination
  • unusual dry mouth/thirst


This drug may rarely cause serious (possibly fatal) liver problems. Tell your doctor right away if you notice any of these rare but serious side effects:

  • dark urine
  • persistent nausea/vomiting
  • severe stomach/abdominal pain
  • yellowing eyes/skin


A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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