Abacavir-Lamivudine Oral

In Depth

Generic Name: ABACAVIR/LAMIVUDINE - ORAL
Pronounced: (a-BAK-a-vir/la-MIV-ue-deen)

Abacavir-Lamivudine Oral Warning

In some patients, the abacavir in this product has caused a serious (sometimes fatal) allergic reaction after the drug is restarted or continued. Symptoms may include any of the following: fever, rash, tiredness, nausea, vomiting, diarrhea, stomach pain, muscle aches, sore throat, mouth sores, swollen glands (lymph nodes), cough, breathing problems. You may still have an allergic reaction to abacavir even if you do not have a rash. If you experience any of these symptoms, contact your doctor immediately. If you have stopped taking abacavir because of an allergic reaction, you must never take any form of abacavir again. Notify all of your doctors and pharmacists if you have stopped taking abacavir due to an allergic reaction. Read the warning card provided with this medication for more details.

Rarely, abacavir/lamivudine has caused a severe (sometimes fatal) liver and blood problem (lactic acidosis). Immediately tell your doctor if you develop symptoms of liver problems (e.g., persistent nausea, stomach/abdominal pain, dark urine, yellowing eyes/skin) or lactic acidosis (e.g., rapid breathing, drowsiness, muscle aches).

If you have hepatitis B infection along with HIV, your hepatitis symptoms may get worse or become very serious if you stop taking abacavir/lamivudine. Talk with your doctor before stopping this medication. Your doctor will perform liver function tests for several months after you stop lamivudine. Tell your doctor immediately if you develop symptoms of worsening liver problems.

Abacavir-Lamivudine Oral Side Effects

See also Warning section.

Trouble sleeping, headache, nausea, diarrhea, stuffy nose, cough, dizziness, weakness or loss of appetite may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

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