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Excedrin Extra Strength Oral

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Excedrin Extra Strength Oral Precautions

Before taking this product, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (e.g., ibuprofen, naproxen, celecoxib); or to acetaminophen; or to caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This product should not be used if you have the following medical condition:

  • aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs such as ibuprofen, naproxen)


Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • asthma
  • certain blood disorders (e.g., anemia)
  • bleeding or blood clotting problems (e.g., hemophilia, low platelet count)
  • ulcers
  • gout
  • poorly controlled diabetes
  • kidney or liver disease
  • growths in the nose (nasal polyps)
  • anxiety disorders
  • insomnia
  • heart disease (e.g., arrhythmia)
  • high blood pressure
  • stomach problems (e.g., heartburn, upset stomach, or stomach pain) that do not go away or persist


Consult your doctor or pharmacist for information on safe use of this product.

Before having surgery, tell your doctor or dentist that you are using this medication.

This product contains acetaminophen, which may cause liver damage. Daily use of alcohol, especially when combined with acetaminophen, may increase your risk for liver damage. Avoid alcohol. Check with your doctor or pharmacist for more information.

This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Avoid alcohol and stop smoking. Consult your doctor or pharmacist for more information.

Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects of the drug, especially stomach problems.

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