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Imavate Oral



Tell your doctor immediately if any of these rare but very serious side effects occur:

  • easy bruising/bleeding
  • signs of infection (e.g., fever, persistent sore throat)
  • severe stomach/abdominal pain
  • dark urine
  • yellowing of eyes/skin


Seek immediate medical attention if any of these rare but very serious side effects occur:

  • chest pain
  • slow/fast/irregular heartbeat
  • fainting
  • seizures
  • slurred speech
  • weakness on one side of the body
  • vision changes


A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Imavate Oral Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (e.g., amitriptyline); or if you have any other allergies.

This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have had:

  • a recent heart attack


Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • breathing problems (e.g., asthma, chronic bronchitis)
  • certain eye problems (e.g., glaucoma, increased intraocular pressure)
  • diabetes
  • eating disorders (e.g., bulimia)
  • heart problems (e.g., arrhythmias, coronary artery disease)
  • liver problems
  • kidney problems
  • personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia)
  • seizures
  • overactive thyroid (hyperthyroidism)
  • trouble urinating (e.g., due to enlarged prostate)
  • any condition that may increase your risk of seizures (e.g., alcohol/sedative dependency, use of electroconvulsive therapy, brain injury/disease such as stroke)
  • certain types of tumors (e.g., pheochromocytoma, neuroblastoma)
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