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Inderide Oral

  • shortness of breath
  • blue fingers/toes
  • swelling ankles/feet
  • mental/mood changes (e.g., depression)
  • numbness/tingling of arms/legs
  • very slow heartbeat
  • decreased sexual ability
  • unexplained/sudden weight gain
  • increased thirst/urination


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • easy bruising/bleeding
  • signs of infection (e.g., fever, persistent sore throat)
  • aching/swollen joints
  • yellowing eyes/skin
  • persistent nausea/vomiting
  • severe stomach/abdominal pain
  • dark urine
  • unusual change in the amount of urine (not including the normal increase in urine when you first start this drug)


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Inderide Oral Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to propranolol or hydrochlorothiazide; or to other thiazides (e.g., chlorothiazide); or if you have had a serious reaction to other beta blockers (e.g., metoprolol, atenolol); or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

  • certain types of heart rhythm problems (sinus bradycardia, second- or third-degree atrioventricular block)
  • severe heart failure
  • asthma
  • an inability to make urine (anuria)


Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • other breathing problems (e.g., bronchitis, emphysema)
  • diabetes
  • heart failure (treated, stable type)
  • other heart problems (e.g., Wolff-Parkinson-White syndrome)
  • overactive thyroid (hyperthyroidism)
  • kidney disease
  • liver disease
  • blood circulation problems (e.g., Raynaud's disease)
  • a certain type of tumor (pheochromocytoma)
  • mental/mood disorders (e.g., depression)
  • certain muscle/nerve disease (myasthenia gravis)
  • high levels of fats in the blood (cholesterol/triglycerides)
  • gout
  • loss of too much body water (dehydration)
  • lupus
  • certain recent nerve surgery (sympathectomy)
  • severe allergic reactions
  • untreated mineral imbalance (e.g., low potassium/magnesium, high calcium)
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