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Ibandronate IV

In Depth

Generic Name: IBANDRONATE - INJECTION
Pronounced: (eye-BAN-droe-nate)

Ibandronate IV Side Effects

Headache, stomach upset, flu-like symptoms (e.g., fever, chills, tiredness, joint/muscle ache), or injection site reactions (e.g., redness, swelling) may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • increased or severe bone/joint/muscle pain
  • jaw pain
  • vision changes
  • change in the amount of urine


A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Ibandronate IV Precautions

Before using ibandronate, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (e.g., alendronate, etidronate, pamidronate, risedronate); or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have the following conditions:

  • low blood calcium levels (hypocalcemia)
  • severe kidney disease


Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • kidney problems


Infrequently, serious jawbone problems (osteonecrosis) have occurred in people taking similar medications. Most people were also using other medications or had conditions that actually caused the jawbone problem. If you have cancer, anemia, blood clotting disorders, infections in the mouth, other diseases of the mouth, or poor dental hygiene, see your dentist for a full examination/treatment before you start ibandronate. Make sure your dentist knows your entire medical history, including any cancer radiation treatments. Also tell your dentist of all the medications you are using, especially cancer chemotherapy and corticosteroids such as prednisone, and tell your dentist you will be using ibandronate. Consult your dentist for more details.

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