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Pamelor Oral

Tell your doctor immediately if any of these rare but serious side effects occur:

  • persistent heartburn
  • shaking
  • mask-like facial expressions
  • muscle spasms
  • severe stomach/abdominal pain
  • decreased sexual ability/desire
  • enlarged/painful breasts


Seek immediate medical attention if any of these rare but very serious side effects occur:

  • severe dizziness
  • fast/irregular heartbeat
  • fainting
  • seizures


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Pamelor Oral Precautions

See also Warning section.

Before taking nortriptyline, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (such as amitriptyline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • breathing problems
  • liver problems
  • recent heart attack
  • problems urinating (such as due to enlarged prostate)
  • overactive thyroid (hyperthyroidism)
  • a certain eye problem (glaucoma)
  • personal or family history of mental/mood conditions (such as bipolar disorder, psychosis)
  • family history of suicide
  • seizures
  • conditions that may increase your risk of seizures (such as other brain disease, alcohol withdrawal)


Nortriptyline may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require immediate medical attention. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may affect the heart rhythm (see also Drug Interactions section). Before using nortriptyline, tell your doctor or pharmacist if you have any of the following conditions:

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