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Oracea Oral

Generic Name: DOXYCYCLINE 40 MG EXTENDED-RELEASE CAPSULE - ORAL
Pronounced: (dox-ee-SYE-kleen)

Oracea Oral Side Effects

Upset stomach, nausea, diarrhea, or mild headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • sunburn (sun sensitivity)
  • difficult/painful swallowing
  • brown/gray tooth discoloration
  • blue/gray/brown discoloration of the skin/lips/tongue/gums
  • unusual tiredness
  • new signs of infection (e.g., fever, chills, persistent sore throat)
  • change in the amount of urine
  • pink urine


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • hearing changes (e.g., ringing in the ears, decreased hearing)
  • easy bruising/bleeding
  • unusual/severe headache
  • vision changes (e.g., blurred vision)
  • severe stomach/abdominal pain
  • persistent nausea/vomiting
  • yellowing eyes/skin
  • dark urine


This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop:

  • persistent diarrhea
  • abdominal or stomach pain/cramping
  • blood/mucus in your stool


Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (fungal infections). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction:

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