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Tolectin Oral

  • easy bruising/bleeding
  • signs of infection (e.g., fever, persistent sore throat)
  • unexplained stiff neck
  • change in the amount/color of urine
  • vision changes


This drug may rarely cause serious, possibly fatal liver disease. If you notice any of the following rare but very serious side effects, stop taking tolmetin and consult your doctor or pharmacist immediately:

  • persistent nausea/vomiting
  • severe stomach/abdominal pain
  • extreme/unusual tiredness
  • weakness
  • dark urine
  • yellowing eyes/skin


A very serious allergic reaction to this drug is rare. However, stop taking tolmetin and immediately seek medical attention if you notice any of the following symptoms of a serious allergic reaction:

  • rash/blisters
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Tolectin Oral Precautions

Before taking tolmetin, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (e.g., ibuprofen, naproxen, zomepirac, celecoxib); or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

  • aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs)
  • recent heart bypass surgery (CABG)


Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • asthma
  • bleeding/clotting problems
  • blood disorders (e.g., anemia)
  • high blood pressure
  • a severe loss of body water (dehydration)
  • diabetes
  • heart disease (e.g., congestive heart failure, history of heart attack)
  • kidney disease
  • liver disease
  • growths in the nose (nasal polyps)
  • obesity
  • tobacco use
  • stomach/intestine/esophagus problems (bleeding sores/ulcer, gastrointestinal bleeding, reflux disease)
  • stroke
  • swelling of the ankles/feet/hands
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