Tykerb Oral
Generic Name: LAPATINIB - ORALPronounced: (la-PA-ti-nib)
Tykerb Oral Warning
Rarely, people taking lapatinib have developed serious (possibly fatal) liver problems. Your doctor will perform liver function tests before and during treatment to monitor for this side effect. Keep all medical/lab appointments. Tell your doctor immediately if you develop symptoms of liver disease such as persistent nausea, stomach/abdominal pain, dark urine, or yellowing eyes/skin. Do not restart this medication if you have previously stopped taking it due to liver problems.
Tykerb Oral Side Effects
See also Warning section.
Nausea, vomiting, upset stomach, mouth sores, mild rash, dry skin, and trouble sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Diarrhea is a common side effect and may become severe. Tell your doctor immediately if diarrhea occurs or if you have signs of a severe loss of body water (dehydration) such as dizziness or decreased amount of urine. Your doctor should prescribe additional medication to help control your symptoms. If your diarrhea becomes severe, your doctor may need to stop or delay your lapatinib treatment.
Treatment with this drug may sometimes cause your hands/feet to develop a skin reaction called hand-foot syndrome (palmar-plantar erythrodysesthesia). Tell your doctor immediately if you experience swelling, pain, redness, peeling, blisters, or tingling/burning of the hands/feet. The symptoms can be made worse by heat/pressure on your hands/feet. Avoid prolonged sun exposure, tanning booths, and sunlamps, as well as unnecessary exposure to heat (e.g., hot dishwater, long hot baths). Use a sunscreen and wear protective clothing when outdoors. Avoid pressure on elbows, knees, and soles of feet (e.g., leaning on elbows, kneeling, taking long walks). Wear loose clothing and comfortable shoes. Depending on how severe your hand-foot syndrome is, your doctor may give you an additional medication to reduce the symptoms, or stop or delay your lapatinib treatment.
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