Estradiol Oral

In Depth

Tell your doctor immediately if any of these unlikely but serious side effects occur:

mental/mood changes (e.g., severe depression, memory loss)
breast lumps
swelling of hands/feet
unusual vaginal bleeding (e.g., spotting, breakthrough bleeding, prolonged/recurrent bleeding)
unusual vaginal discharge/itching/odor
yellowing eyes/skin
stomach/abdominal/pelvic pain
persistent nausea/vomiting
dark urine
worsening of seizures
signs of worsening diabetes control (e.g., increased thirst and urination)

This medication may infrequently cause serious problems such as heart attacks, stroke, and blood clots. Seek immediate medical attention if you experience any of the following:

chest/jaw/left arm pain
sudden severe headache
weakness on one side of the body
confusion
slurred speech
sudden vision changes (e.g., double vision, loss of vision)
pain/redness/swelling of legs
trouble breathing
coughing up blood
sudden dizziness/fainting

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:

rash
itching/swelling (especially of the face/tongue/throat)
severe dizziness
trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Estradiol Oral Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

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