Progesterone Micronized Oral
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (pro-JESS-ter-own)
Progesterone Micronized Oral Warning
Progesterone is sometimes used with another medication (a type of estrogen) as combination hormone replacement therapy (HRT) in women after menopause. Combination HRT can rarely cause very serious side effects such as heart disease (e.g., heart attacks), stroke, serious blood clots (e.g., in the lungs and legs), dementia, and breast cancer. Some of these risks appear to depend on the length of treatment and other factors. Therefore, combination HRT should be used for the shortest possible length of time at the lowest effective dose so you can obtain the benefits and minimize the chance of serious side effects from long-term treatment. Combination HRT should not be used to prevent heart disease or dementia. Discuss the risks and benefits of treatment and your personal health history with your doctor. If you take combination HRT, check with your doctor regularly (e.g., every 3-6 months) to see if you still need to take it.
If you use this medication for an extended period, you should have a complete physical exam at regular intervals (e.g., once a year) or as directed by your doctor. See Notes section.
Progesterone Micronized Oral Side Effects
Nausea, bloating, breast tenderness, headache, change in vaginal discharge, mood swings, blurred vision, dizziness, or drowsiness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these serious side effects occur:
- unusual vaginal bleeding (e.g., spotting, breakthrough bleeding)
- mental/mood changes (e.g., depression, memory loss)
- swelling of the hands/feet
- frequent/burning/painful urination
- breast lumps
- dark patches on the skin or face (melasma)
- yellowing eyes/skin
- stomach/abdominal pain
- persistent nausea/vomiting
- dark urine
- unusual tiredness
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