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Gris-PEG Oral

  • a certain blood disorder (porphyria)
  • severe liver disease (liver failure)


Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • lupus


This drug may make you dizzy or less alert. Do not engage in activities requiring alertness such as driving or using machinery until you know how this drug affects you and that you can safely perform these activities.

Avoid alcoholic beverages while you are taking this drug unless your doctor gives permission. Drinking alcohol during treatment with this drug could result in a fast heartbeat and flushing of the skin.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

This medication is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details and to discuss delaying griseofulvin treatment. Use of reliable form(s) of birth control is recommended during treatment and for 1 month after the drug is stopped. If you are planning to become pregnant within 1 month after treatment, the manufacturer recommends avoiding this drug. (See also Drug Interactions.)

The effects of this drug on human sperm are unknown. However, based on animal cell studies, the manufacturer recommends waiting for a period of time after completing griseofulvin treatment before trying to father a child. Discuss the risks and benefits with your doctor, and ask how long to wait after your last dose before trying to father a child.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

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