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Lamivudine-Zidovudine Oral

  • kidney problems
  • liver problems (such as hepatitis B or C, cirrhosis)
  • disease of the pancreas (pancreatitis)
  • alcohol use
  • low red/white blood cell counts


This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Also limit alcohol because it can increase the risk of liver problems and pancreatitis.

Children may be more sensitive to the side effects of this drug, especially pancreatitis.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

To decrease your risk of spreading HIV disease to others, always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.

During pregnancy, this medication should be used only when clearly needed. However, HIV medicines are now usually given to pregnant women with HIV. Treatment has been shown to decrease the risk of HIV transmission to the baby. Lamivudine/zidovudine may be part of that treatment. Discuss the risks and benefits with your doctor.

Lamivudine and zidovudine pass into breast milk. Because breast milk can transmit HIV, do not breast-feed.

Lamivudine-Zidovudine Oral Medical Alert

Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (US) or 1-800-668-1507 (Canada).

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