Sibutramine Oral

In Depth

Generic Name: SIBUTRAMINE - ORAL
Pronounced: (sye-BYOU-truh-meen)

Sibutramine Oral Side Effects

Dry mouth, increased appetite, nausea, strange taste in the mouth, upset stomach, constipation, trouble sleeping, dizziness, drowsiness, menstrual cramps/pain, headache, flushing, or joint/muscle pain may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

fast/pounding/irregular heartbeat
numbness/tingling of the hands or feet
mental/mood changes (e.g., excitement, restlessness, confusion, depression, rare thoughts of suicide)

Tell your doctor immediately if any of these rare but very serious side effects occur:

change in the amount or color of urine
easy or unusual bruising/bleeding
black stools
vomit that looks like coffee grounds
yellowing eyes or skin
unexplained fever
shaking
unusual sweating
swelling of the arms/legs

Seek immediate medical attention if any of these rare but very serious side effects occur:

seizures
chest pain
weakness on one side of the body
vision changes
trouble breathing

Sibutramine may rarely cause a very serious condition called serotonin syndrome. Taking sibutramine with "triptans" used to treat migraine headaches (e.g., sumatriptan, eletriptan) or certain antidepressants including SSRIs (e.g., citalopram, fluoxetine, paroxetine) and NSRIs (e.g., duloxetine, venlafaxine) increases the risk of this reaction. Before taking sibutramine, tell your doctor if you take any of these medications. Serotonin syndrome may be more likely when you start or increase the dose of any of these medications. Seek immediate medical attention if you develop some of the following symptoms:

severe mental/mood changes (e.g., hallucinations, unusual restlessness)
loss of coordination
fast heartbeat
severe dizziness
unexplained fever
severe nausea/vomiting/diarrhea
twitchy muscles

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: