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Baclofen IT

In Depth

Generic Name: BACLOFEN - INJECTION
Pronounced: (BACK-low-fen)

Baclofen IT Warning

Serious (rarely fatal) problems may occur if you suddenly stop this medication. Seek immediate medical attention if you experience any of the following signs of a withdrawal reaction: high fever, mental/mood changes (e.g., confusion), worsening of muscle tightness/stiffness, itching, dizziness, numbness/tingling of the hands/feet, unusual change in the amount of urine. Special caution is advised for certain patients who are at greater risk (e.g., patients with spinal cord injuries at T-6 or above, trouble communicating, previous withdrawal reaction with oral or injectable baclofen).

To prevent a withdrawal reaction and to make sure that this drug is not suddenly stopped, always keep your scheduled appointments for refilling the pump. Your doctor will check that the pump is programmed and working properly during these appointments. If you must miss a refill appointment, contact your doctor immediately to reschedule the appointment before you run out of medication. Also learn what your pump alarm sounds like. If you hear the alarm, contact your doctor immediately.

Baclofen IT Side Effects

Dizziness, drowsiness, weakness, headache, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • mental/mood changes
  • seizures
  • numbness/tingling of the hands/feet
  • unsteadiness
  • vision changes
  • fainting


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • signs of infection (e.g., fever, chills, redness/swelling at the pump site)
  • unexplained stiff neck
  • severe headache
  • trouble breathing


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

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