Zosyn IV

In Depth

Uses and How to Use
Dosage and Storage
Precautions and Side Effects
Drug Interactions

Generic Name: PIPERACILLIN/TAZOBACTAM SODIUM - INJECTION
Pronounced: (pih-PER-uh-SIL-in/tay-zoh-BACK-tam)

Zosyn IV Side Effects

Swelling, redness, pain, or soreness at the injection site may occur. Dizziness, trouble sleeping, nausea, vomiting, diarrhea, or headache may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

muscle cramps/spasms
swelling of the arms/legs/hands/feet

Tell your doctor immediately if any of these rare but very serious side effects occur:

easy bruising/bleeding
chest pain
confusion
new signs of infection (e.g., fever, persistent sore throat)
severe abdominal/stomach pain
slow/fast/irregular heartbeat
persistent nausea/vomiting
seizures
extreme tiredness
dark/cloudy urine
change in the amount of urine
yellowing eyes/skin

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop:

persistent diarrhea
abdominal or stomach pain/cramping
blood/mucus in your stool

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: