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Kaopectate 1-D (loperamide) Oral

This medication should not be used without seeing your doctor first if you have certain medical conditions. These symptoms/conditions may require other treatment before you can use this medication safely. Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • black/tarry stool
  • blood/mucus in your stool
  • high fever
  • HIV infection/AIDS
  • liver problems
  • certain stomach/intestinal infections (e.g., Salmonella, Shigella)
  • certain type of bowel disease (acute ulcerative colitis)


This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Caution is advised when using this drug in children because they may be more sensitive to the effects of the drug, especially the drowsiness effect. Children are at higher risk for dehydration. (See also Uses, How to Use sections.)

During pregnancy, this medication should be used only if clearly needed. Discuss the risks and benefits with your doctor.

This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

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