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Propafenone Oral

Generic Name: PROPAFENONE - ORAL
Pronounced: (pro-puh-FEN-own)

Propafenone Oral Warning

Although this medication and others like it are used to treat certain kinds of abnormal heartbeats, they may rarely cause serious (sometimes fatal) irregular heartbeats. Therefore, propafenone should be used carefully only in selected patients.

In patients who have had a heart attack, propafenone should be used only with caution. Consult your doctor or pharmacist for more information.

Propafenone Oral Side Effects

See also Warning section.

Dizziness, metallic/salty taste in the mouth, nausea/vomiting, constipation, anxiety, tiredness, shortness of breath, swelling of ankles/legs, and increased infections of the airways (e.g., chest colds) may occur. Less common side effects may also include diarrhea, gas, dry mouth, weakness, and blurred vision. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • fainting
  • sudden change in heartbeat (unusually faster/slower/more irregular)
  • severe dizziness
  • short bursts of pounding heartbeat
  • signs of asthma (e.g., wheezing, persistent/phlegmy cough)
  • worsening symptoms of heart failure (e.g., ankle/leg swelling, increased tiredness, increased shortness of breath when lying down)
  • increased/easy bruising


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • butterfly-shaped facial rash with unusual tiredness and joint/muscle aches
  • signs of serious infection (e.g., high fever, severe chills, weakness, persistent sore throat)
  • signs of liver problems (e.g., persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin, dark urine, severe tiredness)


Propafenone has also rarely caused temporarily decreased sperm counts in men.

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