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Declomycin Oral

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction, including:

  • rash
  • skin sores/blisters
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing
  • new or worsening swelling/pain in the joints
  • chest pain
  • fast/irregular heartbeat


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Declomycin Oral Precautions

Before taking demeclocycline, tell your doctor or pharmacist if you are allergic to it; or to other tetracycline medication (e.g., doxycycline, minocycline, tetracycline); or if you have any other allergies.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • kidney disease
  • liver disease
  • problems swallowing
  • esophagus problems (e.g., esophageal ulcers, hiatal hernia, acid reflux disease-GERD)
  • lupus
  • a certain hormone imbalance called "water diabetes" (diabetes insipidus)


This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

Before having surgery, tell your doctor or dentist that you are using demeclocycline.

This medication should not be used in children younger than 8 years of age because it may cause permanent tooth discoloration and other problems. Tooth discoloration has also occurred in older children and young adults. Consult your doctor for more information.

This medication is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details and to discuss reliable forms of birth control.

This medication passes into breast milk in very small amounts. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

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