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Kidney Transplant
WHAT YOU SHOULD
KNOW
When the kidneys fail, one remedy is to provide a
replacement with a kidney transplant. The new organ, which is
called a "graft" or a donor kidney, may come from someone in
your family (a living related donor) or from someone who has
died (a cadaveric donor). Although your own kidneys are located
in the lower back, the donor kidney will probably be placed in
the lower abdomen, leaving your own kidneys undisturbed. The
operation requires a hospital stay of 1 to 3 weeks.
Rejection is the most common problem with kidney
transplants. Although a donor kidney is chosen to match the
existing kidneys as closely as possible, your immune system is
likely to recognize the difference and attack the new organ as
though it were a foreign invader. To reduce the chance of
rejection, you'll be given large doses of anti-rejection
medicine at the time of the operation and for several months
thereafter. Smaller doses of the medicine will be needed for
life.
IF YOU'RE HEADING FOR THE
HOSPITAL...
Before You Go
-
The Week Before Surgery:
-
You'll probably need to stop
taking aspirin and ibuprofen; the doctor will tell you
when. If you're taking aspirin for your heart, don't stop
without asking the doctor first. Also ask whether you can
take any over-the-counter medicines.
-
Your doctor will tell you
whether you need to have blood drawn.
-
The Night Before Surgery:
-
Your physician may suggest
you take a sleeping pill.
-
Just before surgery, you
should not eat or drink anything (even water). Your doctor
will tell you when to begin fasting.
When You
Arrive
-
Check with your doctor before
taking insulin, diabetes pills, blood pressure medicine,
heart pills, or any other medication on the day of
surgery.
-
Do not wear contact lenses to
the hospital. You may wear glasses.
What to Expect While You're
There
You may encounter the following procedures and equipment
during your stay:
-
Taking Vital Signs: These include your temperature,
blood pressure, pulse (counting your heartbeats), and
respirations (counting your breaths). A stethoscope is used
to listen to your heart and lungs. Your blood pressure is
taken by wrapping a cuff around your arm.
-
Blood Tests: You may need blood taken for tests. It
can be drawn from a vein in your hand or from the bend in
your elbow. Several samples may be needed.
-
Chest X-ray: The surgeon will check this picture of
your lungs and heart to make sure they can tolerate the
operation.
-
Heart Monitor: (Also called an electrocardiogram
[e-LEK-tro-KAR-di-o-gram] or EKG). Typically, three to five
sticky pads are placed on different parts of your body.
Each pad has a wire that is hooked to a TV-type screen or
to a small portable box (telemetry unit) that shows a
tracing of each heartbeat.
-
IV: A tube placed in your vein for giving medicine
or liquids. It will be capped or have tubing connected to
it.
-
Pulse Oximeter: With a little clip connected to your
ear, finger, or toe, this machine measures the oxygen in
your blood.
-
Special Tubes: To help check on your condition, the
following tubes may be inserted in an artery or
vein:
-
Arterial Line: This tube, also called an "art line"
or an "A-line," is inserted into an artery, usually in the
wrist or groin. It can be used to measure blood pressure or
to draw blood for tests. It will be kept filled with liquid
to keep it from getting plugged.
-
Swan-Ganz: This type of tube is threaded into a vein
near your collarbone or neck. It is then guided through
your heart and into your lungs. One end of this tube is
hooked to a machine that monitors the heart. Another part
may be used to give medicine.
-
Cardiac Outputs: These tests show how well your
heart is working. A liquid is pushed very rapidly into the
Swan-Ganz. Doctors then measure the time it takes for this
liquid to move through the heart---an indication of the
heart's pumping capacity.
-
General Anesthesia: To kill pain during the
operation, this medicine is given either as a liquid in
your IV or as a gas through a face mask or endotracheal
(END-o-TRA-kee-ull) tube put down your throat. You will be
completely asleep during surgery.
During Surgery
The surgeon will make an incision in your lower abdomen,
then sew the donor kidney in place and hook it to your blood
vessels. The ureter (outlet tube) of the new kidney will be
hooked to your bladder. At the end of the operation, the
incision will be closed with thread or staples. The surgery
takes between 3 and 4 hours.
After Surgery
Your stitches or staples will be covered with a bandage
to keep the area clean, dry, and free of infection. (A nurse
may briefly remove it soon after surgery to check the
incision.) Immediately after the operation, your family may be
allowed to pay you short visits several times a day. Don't get
out of bed until your doctor say it's OK. You can expect the
following during your recovery.
-
Activity: You'll need to stay in bed for a while
after surgery. But even while you are confined to bed, it's
important to exercise your legs in order to stop blood
clots from forming. Lift one leg off the bed and draw big
circles with your toes, then repeat with the other leg. You
can also try lying on your side and pretending to pedal a
bike. When you're told it's OK to get out of bed, make sure
someone is with you the first time you try. If you feel
weak or dizzy, sit or lie down right away.
-
Day/Night Confusion: Patients in the ICU often can't
tell whether it's day or night, due to round-the-clock
lighting. If you're taken to the ICU to recuperate, you too
may have this problem. However, it will resolve as soon as
you are moved to a regular floor.
-
Deep Breathing and Coughing: These exercises help
prevent a lung infection after surgery. Deep breathing
opens the tubes going to your lungs. Coughing helps to
bring up sputum from your lungs and keep them clear. You
should deep breathe and cough every hour while you are
awake, including any time you spend awake during the
night.
-
Hold a pillow tightly against
your abdomen to help reduce pain from your incision. Take a
deep breath and hold it as long as you can. Then push the
air out of your lungs with a deep strong cough. Put any
sputum that you have coughed up into a tissue. Take 10 deep
breaths in a row every hour while awake. Remember to follow
each deep breath with a cough.
-
Incentive Spirometer (spy-ROM-uh-tur): This piece of
equipment helps you take deeper breaths. Put the plastic
nozzle into your mouth, take a very deep breath, and hold
it as long as possible. Then blow as hard as you can into
the mouthpiece. Take 10 deep breaths in a row every hour
while awake. Remember to follow each deep breath with a
cough.
-
Drains: Thin rubber tubes may be put into the area
around your incision to drain off excess fluid. They will
be taken out when no longer needed.
-
Eating: When your doctor can hear bowel sounds
(stomach growling) through a stethoscope, you'll be able to
eat. You will probably get ice chips first and then liquids
(water, broth, apple juice, or soda). If you do not have
problems with the liquids, you'll then be allowed to eat
soft foods such as ice cream, applesauce, or custard. If
these foods agree with you, you can return to a regular
diet.
-
Bowel Movements: Regular bowel movements can be
difficult after surgery. Don't strain if the stool is too
hard. Walking will help to stimulate the bowels. Eating
foods rich in fiber, such as fruit, bran, cereal, and
beans, will also help restore regularity. Drink plenty of
liquids; prune juice may help make the stool softer. Or, if
your doctor approves, you can take an over-the-counter
fiber laxative.
-
Foley Catheter: This is a tube that is sometimes
inserted into the bladder to drain your urine. The catheter
may make you feel as though you have to urinate. Relax and
the catheter will drain the urine for you.
-
Liquid may be run through the
catheter to clean out blood clots after the operation---a
procedure that sometimes causes painful cramps. If this
happens, don't hesitate to tell the doctor, so that your
pain medicine can be increased.
-
Don't pull on the catheter
because this could cause injury.
-
Don't kink the catheter; this
will stop the flow.
-
Don't lift the bag of urine
above the catheter. If you do, the urine will flow back
into your bladder, possibly causing an
infection.
-
The catheter will be taken
out when you can urinate on your own.
-
Medicines:
-
Anti-Rejection Medicines: (Also called
immuno__suppressives [IH-mew-no-suh-PREH-sivs].) These
medicines discourage your body's immune system from
attacking the new kidney. Although you will probably need
large doses at first, the amount you will need to take on a
permanent basis is generally much smaller.
-
Antacids: Anti-rejection medicine can stimulate
production of stomach acid, leading to indigestion and even
ulcers. Your doctor will probably prescribe an antacid to
keep the acid in check. Take the antacid between meals
right before your medicines. Do not take it with
meals.
-
Antibiotics: These medicines help prevent bacterial
infection, which is a real danger while you are taking
anti-rejection drugs. The antibiotics may be given by IV,
as a shot, or by mouth.
-
Anti-Fungal Medicine: Immunosuppressive drugs also
make you susceptible to fungal infections. To fight them,
anti-fungal medicines may be given in your IV, by mouth, or
as a cream.
-
Pain Medicine: To ease pain after the operation,
your doctor will probably prescribe medication to be given
by IV, as a shot, or by mouth. Tell the doctor or your
nurses if the pain won't go away or keeps coming
back.
-
Anti-Nausea Medicine: This medicine calms your
stomach and controls vomiting. Your doctor may suggest you
take it at the same time as your pain medicine, which
sometimes upsets the stomach.
-
Diuretics (DI-u-REH-tiks): (Often called "water
pills") Fluid may build up in the body while the new kidney
is becoming established. Diuretics help rid the body of
this extra fluid. They can be given as a pill or in your
IV. They will make you urinate more
frequently.
-
Stool Softeners: These medications make bowel
movements softer so you won't need to strain.
-
Heat: After the first 24 to 48 hours you may use
heat for pain or swelling. Use a heating pad (turned on
low) or a hot water bottle, or sit in a warm water bath for
15 to 20 minutes out of every hour as long as you need
relief. Do not sleep on the heating pad or hot water
bottle. Heat brings blood to the area of the surgery and
helps it heal faster.
-
Nasogastric Tube: This type of tube, also called an
NG tube, is threaded through your nose and throat and down
into your stomach. It is attached to suction, which will
keep your stomach empty. It may also help to get your
bowels working. Food or medicine is sometimes given through
the tube.
-
Nuclear Medicine Scan: This special x-ray machine
uses a computer to take pictures of the new kidney. Before
the scan, you'll be given a small amount of radioactive dye
through your IV to make the donor kidney show up better in
the pictures. People who are allergic to shellfish
(lobster, crab, or shrimp), may be allergic to this dye. If
you have this allergy, be sure to warn the
doctor.
-
Oxygen: At times during your stay, your body may
need extra oxygen. It is given either through a plastic
mask over your mouth and nose or through nasal prongs. If
the oxygen dries out your nose or the nasal prongs bother
you, tell your nurse, but don't take off the oxygen on your
own.
-
Pressure Stockings: These tight elastic stockings
keep blood from collecting in the legs and causing
clots.
-
Pneumatic Boots: For extra insurance against blood
clots, these plastic boots or leggings are applied over
pressure stockings or ace wraps and connected to an air
pump machine. The pump rhythmically tightens and loosens
different parts of the boots, helping to push the blood
back up to the heart.
-
Strict Intake/Output: Your doctor may need to know
the amount of liquid you are taking in versus the amount
you lose in your urine. This is often called an
"I&O."
-
Unless told otherwise, drink
6 to 8 large glasses of water each day. Keep a record of
exactly how much liquid you drink.
-
Your output of urine may have
to be measured. Ask your doctor whether it's OK to use the
toilet.
-
Ultrasound: This painless test uses sound waves to
build a picture of internal organs such as the new kidney.
The picture shows up on a TV-like screen.
After You
Leave
-
Be sure to take your
anti-rejection medicine without fail. Do not change the
amount, type of medicine, or time that you take it unless
your doctor tells you to. You must take this medicine for
the rest of your life. If you stop even briefly, you're
likely to lose the new kidney.
-
Every week, check how much
medicine you have left. Refill your prescription when
you're down to a 1- to 2-week supply. It may be easier to
get all your medicines from the same drug
store.
-
If you forget a dose of your
anti-rejection medicine, do not double the next dose. Just
return to your regular schedule. Call your doctor if you
forget more than 1 dose.
-
You may be given steroid
medicine to reduce inflammation of the donor kidney.
Steroids often cause side effects such as a "moon face" and
other changes in your face, abdomen, and back. Even if
these side effects develop, continue taking the steroids
until your doctor says it's OK to stop. Abrupt withdrawal
of the steroids can cause problems.
-
If your doctor has prescribed
antibiotics, use up the entire prescription, even if you
begin to feel better. Stopping the drug too soon can allow
a few hardy germs to survive and re-infect
you.
-
Ask your doctor before taking
any over-the-counter medicine.
-
Anti-rejection medicine may
cause cataracts. Be sure to get an eye exam every 6 months
to help keep your vision at its best.
-
Steroid medicine can increase
your appetite and cause weight gain. Try to keep your
weight under control. Extra weight can increase blood
pressure and lead to heart disease.
-
Fluid build-up can also cause
a sudden gain in weight. Weigh yourself on the same scale
every morning before dressing. Call your doctor if you gain
more than 3 pounds in one day.
-
Your medicine may cause skin
problems. You may find that you bruise easily or develop a
rash or acne on your face, chest, or back. Ask your doctor
if you get a rash or acne. Always wear a 15 SPF or higher
sunscreen when going outside.
-
Because anti-rejection
medicine and steroids will lower your resistance, avoid
people who have an infection such as colds or the flu. Also
try to stay away from large groups. Consider getting shots
to prevent flu and pneumonia.
-
Take your blood pressure
twice each day. Rest at least 5 minutes beforehand. Take it
at the same times each day and in the same
position---either sitting, lying, or standing. Call your
doctor if the reading goes up.
-
Take your temperature every
morning before you get out of bed. Call your doctor if you
are running a high temperature.
-
Always urinate into a
container and measure and record the amount before flushing
it down the toilet. If you urinate during the night,
measure this, too. At the end of each 24 hours, add up all
the numbers. This is called your daily urine output. Call
your doctor if it is less than 20 ounces.
-
In a notebook, jot down the
following things each day: weight, blood pressure, and
daily urine output. Bring this notebook with you to your
appointments with your doctor.
-
When you are allowed to bathe
or shower, carefully wash the stitches or staples with soap
and water and then put on a clean, new bandage. Change the
bandage any time it gets wet or dirty.
-
Do not lift anything heavier
than 10 pounds for 6 weeks after surgery.
-
Slowly start to do more each
day and rest when needed. Once you feel stronger, start a
regular exercise program, gradually increasing the
difficulty. Ask your doctor for an exercise plan. Working
out will make the heart stronger and lower your blood
pressure.
-
Do not drive a car for 8
weeks after surgery. Put a small soft pillow over your
incision before closing your seat belt. Keep the seat belt
loose.
-
Wait 6 weeks after surgery
before having sex. If you are a woman, use birth control
because a pregnancy could put your new kidney at
risk.
-
You may be able to return to
work 6 to 8 weeks after surgery, depending on such factors
as your age and the type of job you have. Your other
medical problems will also affect when you can go back to
work. Talk with your doctor to decide what is best for
you.
-
Drink 6 to 8 large glasses of
liquid, such as water, juices, and milk, each day unless
your doctor says otherwise. Limit caffeinated beverages,
such as coffee, tea, and soda.
-
You should not drink alcohol
for 1 year after your transplant. It is best if you do not
drink alcohol at all. On special occasions, limit yourself
to 1 glass of wine or beer.
Call Your Doctor
If...
-
You have tenderness over the
new kidney area.
-
Your incision is swollen or
red, or has pus coming from it. This is a sign of
infection.
-
Your stitches or staples come
apart.
-
Your bandage becomes soaked
with blood.
-
You are running a high
temperature.
-
Your blood pressure is
high.
-
You have pain or burning when
urinating.
-
Your daily urine output is
less then 20 ounces.
-
You gain more than 3 pounds
in 24 hours.
-
You have diarrhea or vomiting
for more than 24 hours.
-
You have a cough or sore
throat.
-
You have sores in or around
your mouth.
-
You develop sores in the area
between your legs.
-
Your ankles become swollen (a
sign of fluid build-up).
-
Your skin becomes itchy or
swollen, or you develop a rash. This could be sign of
allergy to one of your medicines.
-
You feel that something is
not right in your body. This may be the first sign that
something is wrong with your new kidney.
Seek Care Immediately
If...
-
You suddenly have trouble
breathing. This could be a warning of a blood clot in your
lung or an allergy to one of your medicines.
-
You are too dizzy to stand
up.
-
You feel as though you are
going to pass out.
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