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Ovarian Cancer

WHAT YOU SHOULD KNOW

Compared with more common problems such as breast cancer, ovarian cancer is relatively rare. The chances of developing it are 1 in 100. Like all cancers, the disease is the result of unrestrained multiplication of cells. Normal cells divide in a planned way, creating more cells only when needed. Cancerous cells grow and divide without control or order, often making excess tissue that becomes a tumor. Cancer cells may grow into nearby healthy tissue, or they may break away from the tumor and travel through the blood stream or lymphatic system to other parts of the body, such as the liver, bone, or brain. Ovarian cancer is dangerous because it's very hard to detect in its early stages. The two almond-sized ovaries are located on either side of the uterus deep within the abdomen, where it's impossible to detect a tumor (lump) through self-examination. So by the time symptoms appear, the cancer has often had time to spread.

Causes

Although the exact cause is unknown, several factors make ovarian cancer more likely:
  • A family history of ovarian or uterine cancer, especially in your mother or a sister
  • Late menopause
  • Never being pregnant, or having your first pregnancy after age 30
  • Having had breast cancer or breast disease
  • Having had large bowel cancer or polyps

Signs/Symptoms

During its early stages, ovarian cancer is usually symptom-free. Later, the warning signs may include:
  • Abdominal swelling
  • Bloating
  • Stomach discomfort
  • Lack of appetite
  • A feeling of fullness after even a small meal
If the tumor is large, it may push on other organs causing diarrhea, constipation, or frequent urination.

Care

The doctor's first step will be to determine how far the cancer has advanced. He will probably take a tissue sample and perform tests such as an ultrasound, CAT scan, and special x-rays to check other organs. The results of the tests will help you and the doctor choose a treatment plan. Many types of treatment are available; and depending on the stage of the cancer, several may be combined. The most common options for ovarian cancer are:
  • Surgery: An operation is almost always the first step in treatment, because the cancerous tissue must be removed. You may also need to have some lymph nodes taken out to help prevent the cancer from spreading to other parts of your body.
  • Chemotherapy: Often called "chemo," this type of therapy uses drugs to kill new tumor cells or shrink lymph nodes that contain cancer cells. It may be used after surgery to kill any cancer cells undetected during the operation. Many different chemo medicines are available. They may be taken as a pill, as a shot, or in an IV. You will probably need frequent blood tests to determine how your body is doing and how much chemo you need. The drugs can produce many side effects, and may leave you susceptible to infection for a while.
  • Radiation: X-rays or gamma rays can kill cancer and help prevent it from spreading. They can also be effective in reducing pain, controlling bleeding, and shrinking cancerous tumors. Doctors also use this type of therapy on cancerous lymph nodes. Radiation and chemotherapy are often used together. Radiation is also used after surgery to kill any cancer cells that may have been missed.
  • Biologic Therapy (also called biotherapy or immunotherapy): This type of treatment relies on special drugs that boost the immune system to help your body fight growing cancer cells. Certain drugs may also make cancer cells weaker and easier to kill. The medications are usually given through an IV. They may cause flu-like symptoms.
  • Paracentesis: If the tumor causes extra fluid to collect in the abdomen, the doctor can remove it with a needle. This procedure will make you more comfortable and may make it easier to breathe.

Risks

If the cancer is not treated, it is certain to spread. All forms of treatment have unpleasant side effects, and in the end, may still fail to halt the spread. Nevertheless, some form of treatment is your only chance of a cure.


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