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Vitiligo

WHAT YOU SHOULD KNOW

People with vitiligo develop stark white skin patches on various parts of the body. These patches typically appear on the face, over bony surfaces such as the elbows and knees, and on the hands, feet and genitalia. The hair within these patches is also likely to turn white. The condition typically affects people between the ages of 10 and 30, but it shows no racial or gender preference.

Causes

The whiteness seen in vitiligo is due to the destruction and loss of pigment cells (melanocytes) in the skin. Why this occurs is unknown, but it is more likely to happen in people with diabetes, pernicious anemia, thyroid problems, or poorly functioning adrenal glands. The problem sometimes sets in following a physical trauma, particularly a blow to the head.

Signs/Symptoms

The white patches produced by vitiligo usually have sharp boundaries, and are often symmetrical. The problem may be limited to a few small spots or may spread to cover almost the entire body. The whitened areas are prone to sunburn and, in a few people, may itch. The condition is sometimes accompanied by premature graying of the hair.

Care

Vitiligo is usually treated with repigmentation therapy. Treatments for small areas typically involve application of a medicated cream or liquid followed by 90 minutes under a ultraviolet A lamp. Larger areas are treated with an oral medication and ultraviolet A. Localized treatments may continue for up to 2 months at a time. Treatments for widespread vitiligo may go on for 1 to 2 years.

People with vitiligo over more than half of their body sometimes opt for depigmentation therapy, in which a cream is applied to unaffected skin to destroy pigment cells and create an even skin tone. This form of treatment, however, is permanent and causes extreme sensitivity to sunlight.

For people who can't tolerate repigmentation therapy or don't respond to it, there are cosmetic cover-up creams and tanning lotions that successfully hide the problem without soiling clothing.

Risks

Aside from the emotional distress caused by a change in appearance, there are no known health risks associated with vitiligo.

WHAT YOU SHOULD DO

  • Avoid sun exposure. The vitiligo patches have no pigmentation to protect you from sunburn and potential skin cancer. When you are in the sun, use a high SPF sunblock.
  • If you choose repigmentation therapy, take your medications exactly as prescribed by your doctor.
  • If you plan to be in sunlight after being exposed to ultraviolet light, apply sunscreen.
  • If sunburn occurs, discontinue therapy temporarily and apply wet dressings to the affected areas for 15 to 20 minutes four or five times a day. Afterwards, allow the skin to air dry and apply a lubricating cream while the skin is still moist.



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