Cymbalta
Also see more information on Cymbalta Oral from the
First Databank
drug library.
Brand name:
Cymbalta
Pronounced: sim-BALL-ta
Generic name: Duloxetine hydrochloride
Why is Cymbalta prescribed?
Cymbalta is used to treat major depression--a disorder marked by
continuing, serious, and overwhelming feelings of depression that
interfere with daily functioning. Symptoms may include major
changes in appetite or sleep habits; lack of interest in social or
work life; feelings of sadness, guilt, or worthlessness; fatigue;
difficulty concentrating or making decisions; and suicidal thoughts
or attempted suicide.
Cymbalta is also used to treat diabetic peripheral neuropathy, a
painful nerve disorder associated with diabetes that affects the
hands, legs, and feet.
Cymbalta is thought to work by correcting an imbalance of two
brain chemicals known to influence mood--serotonin and
norepinephrine. It belongs to a class of antidepressants called
selective serotonin and norepinephrine reuptake inhibitors
(SNRIs).
Most important fact about Cymbalta
Serious, sometimes fatal reactions can occur if Cymbalta is
taken with antidepressants known as MAO inhibitors, including
Marplan, Nardil and Parnate. Never combine Cymbalta with one of
these drugs, and wait at least 14 days after stopping an MAO
inhibitor before starting treatment with Cymbalta. Likewise, after
stopping therapy with Cymbalta, allow at least 5 days before
starting treatment with an MAO inhibitor.
How should you take Cymbalta?
Take Cymbalta at about the same time each day. Swallow the
capsule whole; do not chew it or break it open. Cymbalta may be
taken with or without food.
It may take several weeks before the drug begins to work.
Continue taking Cymbalta even if you begin to feel better. Do not
stop taking this drug without your doctor's approval. Abruptly
stopping treatment may cause severe side effects.
--If you miss a dose...
Take the forgotten dose as soon as you remember. However, if it
is almost time for your next dose, skip the one you missed and
return to your regular schedule. Do not take two doses at once.
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