Activella and femhrt

Generic ingredients: Estrogen, Progestin
Other brand name: Prefest

Why is Activella and femhrt prescribed?

These medications are designed for use in hormone replacement therapy. Both combine a form of estrogen with a substance that acts like progesterone. Both relieve the symptoms of menopause, and both are prescribed to prevent osteoporosis in postmenopausal women. (Activella is also used for vaginal atrophy.)

Estrogen, when taken by itself, poses an increased risk of uterine cancer. The progestin in these products largely counteracts this effect.

Most important fact about Activella and femhrt

Because of the risk of uterine cancer, be sure to alert your doctor if you experience any abnormal vaginal bleeding. There is little, if any, increase in risk during the first year of treatment, but the odds rise substantially after 5 to 10 years.

How should you take Activella and femhrt?

Take one tablet at the same time each day, with or without food. If you are taking the medication to relieve menopausal symptoms, your doctor will reevaluate your need for medication every 3 to 6 months. If you are taking the product to prevent osteoporosis, you will probably continue for years.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

--Storage instructions...

Store at room temperature. Keep Activella in a tightly closed container away from moisture and light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this type of product.

• More common side effects may include:
  Abdominal pain, breast tenderness and enlargement, depression, enlargement of uterine fibroids, headache, nausea, nervousness, skin reddening, urinary tract infection, vaginal inflammation, vomiting

Why should Activella and femhrt not be prescribed?

Do not take these products if you have:

• Known or suspected breast cancer, any other cancer stimulated by estrogen, or a past history of breast cancer associated with estrogen use
• Unexplained genital bleeding
• A history of blood clots or phlebitis
• Sensitivity to estrogen or progesterone
• Any reason to believe that you are pregnant